Syria: Apamea ruins. Apamea is located on the right bank of the Orontes river about 55 km to the north west of Hama. It overlooks the Ghab valley and was built by Seleucus Nicator, the first king of the Seleucids in Syria in 300 BC. He named it after his parisian wife, Apamea. Most of the uncovered ruins in it date back to the Roman and Byzantine ages.