Two Blister Beetles Mating (You Can See How The Top One Open His Mouth Screaming). Blister beetles are beetles (Coleoptera) of the family Meloidae, so called for their defensive secretion of a blistering agent, cantharidin. Many are conspicuous and some aposematically colored, announcing their toxicity to would-be predators. Cantharidin is a poisonous chemical that causes blistering of the skin.

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